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"Oleogel" Dosage Formulation of Azithromycin in Healthy Adult Volunteers
"Oleogel" Dosage Formulation of Azithromycin in Healthy Adult Volunteers
Some children and adults have trouble swallowing tablets. In some areas, there is no easy access to clean water to help swallow them. Help us evaluate the safety and absorption of the new gel-like "Oleogel" formulation of Azithromycin.
18-45 years • Any Sex/Gender
Carlo Giovanni Traverso, PhD, MB BChir
Brigham and Women's Hospital
Recruiting Middle/ High Schoolers to Test a New Drug Education Curriculum
Recruiting Middle/ High Schoolers to Test a New Drug Education Curriculum
The Center for Addiction Medicine has developed a new drug curriculum for teenagers. We're recruiting students who have violated their schools' substance use policies in the past month to complete study visits and to test out this program.
10-22 years • Any Sex/Gender
Randi Schuster, PhD
Massachusetts General Hospital
Do you or a loved one experience psychosis associated with Alzheimer's Disease?
Do you or a loved one experience psychosis associated with Alzheimer's Disease?
This study focuses on on an investigational drug and its effects and safety on older adults who are experiencing psychosis associated with Alzheimer's disease.
55-90 years • Any Sex/Gender
Arkadiy Stolyar, MD
McLean Hospital
Adults with Food Allergy Needed for Drug Clinical Trial!
Adults with Food Allergy Needed for Drug Clinical Trial!
Do you have a severe food allergy? We are researching the safety and tolerability of an experimental drug when combined with another drug for adults ages 18 to 50 with severe food allergies.
18-50 years • Any Sex/Gender
Sarita Patil, MD
Massachusetts General Hospital
Have you been diagnosed with atherosclerotic cardiovascular disease (ASCVD)?
Have you been diagnosed with atherosclerotic cardiovascular disease (ASCVD)?
The REMBRANDT study will assess the impact of an investigational drug, obicetrapib, in people with ASCVD, a condition where blood vessels supplying the heart are narrowed or blocked.
45-years or older • Any Sex/Gender
Diana M Lopez, MD
Brigham and Women's Hospital
Chronic Rhinosinusitis with Nasal Polyps Clinical Research Study: DUET
Chronic Rhinosinusitis with Nasal Polyps Clinical Research Study: DUET
Are you between the ages 18-70 and are experiencing chronic rhinosinusitis with nasal polyps (CRSwNP)? This study is evaluating the safety and efficacy of a study drug called lunsekimig compared to placebo.
18-70 years • Any Sex/Gender
Stella Lee
Brigham and Women's Hospital
Rhinosinusitis with nasal polyps clinical study: CONTRAST-NP
Rhinosinusitis with nasal polyps clinical study: CONTRAST-NP
Do you have nasal polyps but are looking for an alternative to surgery? This study is evaluating the safety and efficacy of a study drug called lebrikizumab compared to placebo.
18-years or older • Any Sex/Gender
Stella Lee
Brigham and Women's Hospital
Inhaled Clofazimine for Nontuberculous Mycobacterial Lung Infection (NTM) Clinical Trials
Inhaled Clofazimine for Nontuberculous Mycobacterial Lung Infection (NTM) Clinical Trials
ICoN-1is a research study to evaluate the safety and efficacy of study drug Clofazimine Inhalation Suspension for those diagnosed with Nontuberculous Mycobacteria (NTM) lung disease. Clofazimine Inhalation Suspension is an antibiotic.
18-85 years • Any Sex/Gender
John Albin, MD, PhD
Massachusetts General Hospital
Do you have Hidradenitis Suppurativa (HS)?
Do you have Hidradenitis Suppurativa (HS)?
We are studying how safe and effective an oral investigational medication may be in treating participants living with HS.
12-years or older • Male, Female
JiaDe Yu, MD, MS
Massachusetts General Hospital
Struggling to relieve your depression symptoms?
Struggling to relieve your depression symptoms?
The purpose of this clinical research study is to determine the safety and effectiveness of a potential new study drug for the treatment of Major Depressive Disorder (MDD).
18-65 years • Male, Female
Joshua Salvi, MD PhD
Massachusetts General Hospital
Healthy Adults Ages 18-35 Wanted for Brain Imaging Study on Epigenetics and Socio-emotional Behavior
Healthy Adults Ages 18-35 Wanted for Brain Imaging Study on Epigenetics and Socio-emotional Behavior
We are recruiting young, healthy adults for a PET/MRI study investigating how epigenetics (the process through which environment influences how genes are read) in the brain is associated with social and emotional behaviors.
18-35 years • Male, Female
Nicole R Zürcher, PhD
Massachusetts General Hospital
Have you been diagnosed with Hypothalamic Obesity?
Have you been diagnosed with Hypothalamic Obesity?
In the RM-718-001 study, we will investigate the safety and tolerability of RM-718 study drug and its effects on weight, waist circumference and hunger.
18-65 years • Male, Female, Transgender Female, Transgender Male, Nonbinary, Intersex, Gender-expansive
Vanita Aroda, M.D.
Brigham and Women's Hospital
Do you or a loved one experience agitation associated with ALZHEIMER'S DISEASE-RELATED DEMENTIA?
Do you or a loved one experience agitation associated with ALZHEIMER'S DISEASE-RELATED DEMENTIA?
This study will test the safety, tolerability, and effectiveness of NMRA-323511, a new drug designed to help manage agitation in people with Alzheimer's disease.
55-90 years • Male, Female, Transgender Female, Transgender Male, Nonbinary, Intersex, Gender-expansive
Arkadiy S Stolyar, MD
McLean Hospital
Are you experiencing Ulcerative Colitis symptoms? Join our clinical drug trial!
Are you experiencing Ulcerative Colitis symptoms? Join our clinical drug trial!
We are looking for adults ages 18 to 75 with active mild ulcerative colitis for a research study exploring the use of an investigational drug to address the underlying causes of disease onset and progression.
18-75 years • Any Sex/Gender
Joshua Korzenik, MD
Brigham and Women's Hospital
Recently started Suboxone? You may be eligible for a study about Ozempic!
Recently started Suboxone? You may be eligible for a study about Ozempic!
We are doing this research to understand the safety, efficacy, tolerability of and potential ways that semaglutide can play a role in the treatment of opioid use disorder.
18-years or older • Any Sex/Gender
Joji Suzuki, MD
Brigham and Women's Hospital
ML-004 in Adolescents and Adults With Autism Spectrum Disorders (ASD)
ML-004 in Adolescents and Adults With Autism Spectrum Disorders (ASD)
In this study, we are looking to find out whether an investigational drug, ML 004, might improve the symptoms of ASD that often make social interaction challenging.
12-17 years • Any Sex/Gender
Usman Ghumman, MD, MPH
Massachusetts General Hospital
Participants needed to advance a therapeutic treatment for celiac disease
Participants needed to advance a therapeutic treatment for celiac disease
We are studying the inhibitory effects of the drug Ritlecitinib on inflammatory pathways in patients with celiac disease. This study will help us understand the efficacy of medicinal treatments in people with celiac disease.
18-75 years • Any Sex/Gender
Alessio Fasano, MD
Massachusetts General Hospital
Psilocybin Assisted Psychotherapy Among Adult Patients with Irritable Bowel Syndrome
Psilocybin Assisted Psychotherapy Among Adult Patients with Irritable Bowel Syndrome
We are studying an investigational drug, psilocybin, in conjunction with psychotherapy for irritable bowel syndrome. Study participants will receive multiple psychotherapy sessions, including two psilocybin-assisted psychotherapy sessions.
21-74 years • Any Sex/Gender
Franklin King, MD
Massachusetts General Hospital
Medication Study for Adults with High Blood Pressure
Medication Study for Adults with High Blood Pressure
The purpose of this study is to see whether, in people with high blood pressure, the drug eplerenone can make the heart and blood vessels work better than the drug chlorthalidone. Both medications are FDA-approved.
18-75 years • Male, Female
Gail K Adler, MD, PhD
Brigham and Women's Hospital
Xenon gas inhalation study in healthy volunteers
Xenon gas inhalation study in healthy volunteers
Current Alzheimer's disease (AD) treatments are only partially effective. This proof-of-concept investigation may provide valuable insights to develop new therapies. This goal of this study is to assess the safety of xenon gas inhalation.
55-75 years • Male, Female
Howard Weiner, MD
Brigham and Women's Hospital
Try Bezafibrate - a new treatment drug for Bipolar Depression
Try Bezafibrate - a new treatment drug for Bipolar Depression
This is a new medication study that looks into whether Bezafibrate can be used as an effective drug treatment for bipolar depression.
18-65 years • Male, Female
Andrew A Nierenberg, MD
Massachusetts General Hospital