Note: This study is currently only recruiting patients in the hospital.
If you are interested in being notified if this study begins recruiting from the general population, please use the 'I Am Interested' button below.
Help Us Learn More About the Effect of Light Exposure at Night on the Body!
This project is not recruiting.
Overview
What we are studying
In this research study we want to learn more about how insufficient sleep night after night adversely impacts metabolism, and how exposure to artificial light at night plays a role.
Why it is important
This project is designed to test for the first time whether glucose metabolism is differentially impaired by sleep restriction with and without additional exposure to artificial light at night (ALAN). Laboratory studies have shown that sleep restriction to 4-6h per night for durations varying from one to 14 days reduces glucose tolerance in otherwise healthy adults, but the mechanisms by which insufficient sleep impairs glucose metabolism are still unknown. Current theories are based on the premise that the adverse metabolic consequences are caused by reduction in the duration of sleep per se. However, sleep curtailment is typically accompanied by longer exposure to artificial light at night (ALAN), which is an environmental endocrine disrupter that profoundly disrupts circadian rhythms
What we hope to accomplish
The goal of this project is to evaluate whether extended duration artificial light at night (ALAN) contributes to the adverse effects of sleep restriction on glucose metabolism.
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Principal Investigator
Who can participate
Healthy Participants who are: - 20-40 years of age - non-smokers - not taking any medication - are willing to abstain from use of caffeine, nicotine, and alcohol during study screening and during the study itself - individuals with a BMI of < 25 - must be willing to spend the duration of the study (33 days and nights) living in the clinical research center
Healthy Volunteers
Healthy volunteers are eligible for this study
What you may be asked to do
If you decide to join this research study, the following things will happen:
Project activities may include:
- Blood draw
- Injection or IV
- Overnight stay
- Survey
- Office visit
- X-ray
Estimated Time Commitment
33 days
What You May Get
You will be paid $125 if you complete all screening procedures. You will be paid $200 per day for each of
the 33 days of the inpatient study. You will be paid a $2,500 bonus if you complete the entire study. If you
do not complete the study, you will be paid for the parts of the study you have completed, but you will not
get any study bonus. If you complete the entire 33-day study, you will receive $9,225. It will take several
weeks from the time the study ends to process the request for the check and for the check to be mailed
to you.
Location
Travel
- Accessible by public transportation
- Parking available
- Local travel reimbursed
Travel and Parking Details
Study screening visits will be conducted at the Boston Lying In Hospital (part of BWH), 221 Longwood Avenue. Valet services are available for in-person study screening visits. The main study is conducted at the main hospital, 75 Francis Street. Because participants are asked to stay for 33 days as an inpatient, parking is not available for this visit. Instead, participants will be asked to either get a ride, take public transportation, or take a taxi/ride service to and from the study. Travel to and from the study may be reimbursed.
Additional Information
Funding Source
- NIH or Other Federal