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Note: This study is currently only recruiting patients in the hospital.

If you are interested in being notified if this study begins recruiting from the general population, please use the 'I Am Interested' button below.

Do you drink coffee or tea? Looking for volunteers for a study on caffeine and brain function.

The Wey research group at Massachusetts General Hospital is conducting a research study to understand the effects of caffeine on learning.

6 hours over 2 visits
Estimated Time Commitment
Any Sex/Gender, 18-45 years
May Be Eligible
Payment up to $610
May Be Offered
Blood draw, Injection or IV, Survey, Office visit, MRI scan, PET scan
May Be Required
 
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This project is not recruiting.

What we are studying

This study will determine if and how consuming caffeine affects the learning process through reward feedback. The data acquired from this study would improve our understanding on the consequences and mechanism of caffeine intake on learning.


Why it is important

Caffeine is a popular substance, but relatively little is understood when it comes to how it affects the brain dynamics underlying reward-driven behavior.


What we hope to accomplish

Our hope is that this study will allow us to better understand the dynamics of learning in the human brain and how caffeine affects this process.

Principal Investigator

Hsiao-Ying Wey, PhD

Massachusetts General Hospital

Public Profile

Healthy adults between the ages of 18 and 45 who habitually consume caffeine.


Healthy Volunteers

Healthy volunteers are eligible for this study

Pregnant or lactating women
Women using a form of hormonal birth control
Anyone with a BMI below 18.5 or above 29.9
Those with active substance abuse disorders
Anyone who has been diagnosed with depression, anxiety, psychosis, or other neurological disorders within the last 5 years.
Anyone who had been diagnosed with a cardiovasucular disease (e.g., heart disease)
Anyone who had been diagnosed with a metabolic disease (e.g., diabetes)

Undergo a simultaneous PET/MRI scan
Medical history and basic physical conducted by nursing staff
Urine drug test


Project activities may include:

  • Blood draw
  • Injection or IV
  • Survey
  • Office visit
  • MRI scan
  • PET scan

Estimated Time Commitment

6 hours over 2 visits


Participants will be compensated up to $610 for completion of the study.

Martinos Center for Biomedical Imaging at MGH East Campus
149 13th Street, Charlestown, MA

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Travel

  • Accessible by public transportation
  • Parking available
  • Parking reimbursed

Travel and Parking Details

Travel to the Charlestown Navy Yard is available via Partners Healthcare shuttles, free-of-charge, from North Station or the main MGH campus


Parking is available on-site 
Parking will be reimbursed


Participating Institutions


Funding Source

  • Department
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