Note: This study is currently only recruiting patients in the hospital.
If you are interested in being notified if this study begins recruiting from the general population, please use the 'I Am Interested' button below.
Are you nearing menopause or currently going through menopause?
Enrollment for this study is expected to close on Wednesday, June 25, 2025
Overview
What we are studying
We are doing this research study to find out how inflammation changes during menopause. The research study will compare changes in inflammation before, during, and after menopause.
Why it is important
Understanding links between inflammation and menopause may help us identify ways to preserve the health of the heart in women.
What we hope to accomplish
We plan to measure changes in inflammation in the blood over one year in women during menopause.
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Principal Investigator
Contact
Click I Am Interested "I Am Interested" "I Am Interested" to get started. If you have questions, contact:
Kamila Bielawski
Who can participate
Adult women age 45-55 years old with high blood pressure and/or obesity who are nearing menopause or currently undergoing menopause who are able to provide informed consent and willing to comply with the study.
Who cannot participate
Pregnant or breastfeeding at time of study visit No clinical history of heart disease including previous heart attack, heart failure, recent stroke Significant valvular disease on transthoracic echocardiogram No history of hysterectomy or bilateral oophorectomy Taking estrogen or progesterone History of long term irregular periods Taking opiate medications long term Major medical problems including liver disease, cancer, or autoimmune diseases
What you may be asked to do
The research study includes two study visits approximately one year apart. During the study visits, eligible participants will undergo a focused physical exam, blood draw, EKG, IV placement, collection of cells from a vein, and a cardiac ultrasound as part of the study visit.
Project activities may include:
- Blood draw
- Injection or IV
- Ultrasound
Estimated Time Commitment
2 visits over 1 year
What You May Get
We will pay you up to $125 if you complete the study. If you do not complete the study, we will pay you as follows:
Visit 1: $50 (+ $20 for voluntary second cell collection)
Visit 2: $75 (+ $20 for voluntary second cell collection)
TOTAL $165
We will also pay for parking in the hospital garage during your visit.
Location
MGH Translational and Clinical Research Center
55 Fruit Street, Boston, MA 02114, White 12
Travel
- Accessible by public transportation
- Parking reimbursed
- Parking available
Travel and Parking Details
Parking in the MGH parking garage will be reimbursed.
Additional Information
Funding Source
- Foundation