Note: This study is currently only recruiting patients in the hospital.

If you are interested in being notified if this study begins recruiting from the general population, please use the 'I Am Interested' button below.

Melatonin Sleep Study needs healthy Caucasian non-smokers between the ages of 21-55!

Studying healthy individuals with genetic variation in MTNR1B, which influences the regulation of blood sugar and has been associated with type 2 diabetes risk.

Brigham and Women's Hospital Diabetes Type 2 Genetic Testing Healthy Living
6 visits
Estimated Time Commitment
Male, Female, 21-55 years
May Be Eligible
Payment up to $3,875, Meals
May Be Offered
Survey, Blood draw, Office visit, Overnight stay, Medication
May Be Required
 
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This project is not recruiting.

Overview

What we are studying

The purpose of the research is to determine the effect of melatonin on how your body processes sugar (e.g. glucose metabolism). We also want to understand if your genes influence this effect of melatonin on your blood sugar. Melatonin is a hormone that is produced by your body especially at night. This study will be performed in healthy individuals with genetic variation in a gene called MTNR1B. This gene influences the regulation of blood sugar and has been associated with type 2 diabetes risk.


Prospective research study participants must be Caucasian non-smokers between the ages of 21-55, and without medication use (birth control is acceptable). To see if you are eligible, please fill out our online survey at (will redirect you to a secure website outside of Rally):


https://redcap.partners.org/redcap/surveys/?s=8PYDFMA7TP 


Why it is important

https://www.youtube.com/watch?v=JBQDOiR9EvU 


What we hope to accomplish

Principal Investigator

Frank AJL Scheer, PhD

Brigham and Women's Hospital

Public Profile

Who can participate

Prospective subjects must be healthy Caucasian non-smokers between the ages of 21-55, live in New England, and off most medications (birth control is acceptable). If interested please fill out: https://redcap.partners.org/redcap/surveys/?s=8PYDFMA7TP 


Healthy Volunteers

Healthy volunteers are eligible for this study

What you may be asked to do

What you may be asked to do


•         Short screening visits


•         One 5-day in-laboratory stay, and/or three 2-day in-laboratory stays at Brigham and Women’s Hospital


•         Melatonin Administration


•         Intravenous Glucose Tolerance Test


•         Biological sample collection (i.e., blood, urine, saliva)


•         Sleep measurements


•         Neurobehavioral Testing


Project activities may include:

  • Survey
  • Blood draw
  • Office visit
  • Overnight stay
  • Medication

Estimated Time Commitment

6 visits

What You May Get

Up to $1,725 for 5-day stay, $2,150 for three 2-day stays, and $3,875 for both protocols

Location

Brigham & Women's Hospital
221 Longwood Avenue

Map it!


Travel

  • Local travel reimbursed
  • Parking available
  • Accessible by public transportation
  • Parking reimbursed

Travel and Parking Details

Additional Information

Project Website

https://j.mp/2BQUoUb


ClinicalTrials.gov Identifier

NCT02642640


Participating Institutions


Funding Source

  • NIH or Other Federal
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