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Note: This study is currently only recruiting patients in the hospital.

If you are interested in being notified if this study begins recruiting from the general population, please use the 'I Am Interested' button below.

Got a baby on board? Can melatonin affect your uterine contractions?

Researchers at Brigham and Women's Hospital are looking for first-time pregnant women, ages 18 to 35 to participate in a 1-night/2-day study on the relationship between melatonin and contractions. You could earn up to $1200.

3 sessions
Estimated Time Commitment
Female, 18-35 years
May Be Eligible
Payment up to $1,200
May Be Offered
Survey, Blood draw, Injection or IV, Office visit, Biosample (e.g., saliva, urine, or stool)
May Be Required
 
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This project is not recruiting.

What we are studying

We want to learn more about how melatonin is related to contraction levels in women who are pregnant with their first child. Previous research has shown that melatonin concentration levels may be related to the number of uterine contractions.


 


Why it is important

We hope that this research will contribute to our collective understanding of the physiological mechanisms for melatonin action in the human uterus.


What we hope to accomplish

Principal Investigator

Elizabeth B Klerman, MD, PHD

Massachusetts General Hospital

Public Profile

We are looking for pregnant women between the ages of 18 to 35 to participate in our study.


Inclusion Criteria:


- First pregnancy


- Single fetus


 


Healthy Volunteers

Healthy volunteers are eligible for this study

This study involves pregnant women in their third trimester (38 weeks and over). You will attend a consent visit and fill out initial questionnaires to see if you qualify for the study. For one week before entering the lab, you will be asked to track your sleep/wake schedule.  Volunteers who complete screening will then participate in a ~40-hour inpatient stay at BWH during which:


1. You will come into the lab for about two days+2 nights


2. You will receive varied light level exposure


3. You will receive a dose of melatonin


4. We will monitor your contractions and give you mood questionnaires.  


5. We will take blood and saliva samples throughout the duration of your stay  


Project activities may include:

  • Survey
  • Blood draw
  • Injection or IV
  • Office visit
  • Biosample (e.g., saliva, urine, or stool)

Estimated Time Commitment

3 sessions


Participants can receive up to $1200

Brigham and Women's Hospital
75 Francis Street

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Massachusetts General Hospital
55 Fruit Street, Boston, MA, 02114

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Travel

  • Accessible by public transportation
  • Parking reimbursed
  • Local travel reimbursed
  • Parking available

Travel and Parking Details

Reimbursed up to $100 for travel and/or parking costs


Funding Source

  • NIH or Other Federal
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