Note: This study is currently only recruiting patients in the hospital.

If you are interested in being notified if this study begins recruiting from the general population, please use the 'I Am Interested' button below.

Do you have PAIN after SHINGLES (postherpetic pain)?

The Translational Pain Research Group at the Brigham and Women's Hospital is seeking volunteers who have pain following shingles to participate in a research study. Volunteers who qualify for the study will be reimbursed for their time.

Brigham and Women's Hospital Pain Shingles
3 hours over 1 visit
Estimated Time Commitment
Female, Male, 18-80 years
May Be Eligible
Payment up to $75
May Be Offered
Survey, Office visit, Biopsy, Blood draw
May Be Required
 
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This project is not recruiting.

Overview

What we are studying

The purpose of the study is to try to find out why some people with nerve disease or dysfunction develop pain and some do not.


Why it is important

The purpose of this study is to try to determine those possible factors that may cause nerve pain, with the long-term goal of developing treatments to target these factors to treat pain.


What we hope to accomplish

We would like to use samples of your blood to study how your genes work. Genes are the parts of each living cell that allow parents to pass on things such as hair color, eye color, and body height to their children. Your genes have been producing certain chemicals and proteins since your nerves were injured. We want to compare how genes work in people with pain and without pain. One way to do this is to look at how some of your blood cells express these genes.



We would like to know how the behavior of genes can lead to pain or prevent pain in people who have suffered from nerve injury. In this study, we will not focus on your genetic make-up (which particular genes you have), but how your genes work. To do this we have chosen to see if there are any differences in the genetic markers of people with nerve damage from other conditions, and healthy volunteers.

Principal Investigator

Christine N. Sang, MD

Brigham and Women's Hospital

Public Profile

Who can participate

We are asking you to take part in this study because you have experienced pain following shingles, also known as postherpetic neuralgia.

Who cannot participate

Because of the genes we are looking at, patients with the following conditions are asked not to participate:



  • Pregnant women or women who are breast-feeding

  • HIV or any current infections

  • End-stage kidney or liver disease

  • Other conditions to be determined upon screening

What you may be asked to do

At different timepoints throughout the visit, the following may be performed:



  • Medical History and Physical Exam

  • Questionnaires

  • Sensory testing

  • Blood draw and Urine tests

  • Electrocardiogram (ECG)

  • Skin biopsy


Project activities may include:

  • Survey
  • Office visit
  • Biopsy
  • Blood draw

Estimated Time Commitment

3 hours over 1 visit

What You May Get

You will receive $75.00 for completing all of the blood draws, questionnaires and sensory testing if you are not participating in a study that includes this procedure.


You will receive an additional $50.00 for each skin punch biopsy that you complete.


We will reimburse you up to $25.00 per visit for parking in the hospital garage or local public transportation to study visits. To be reimbursed, you will need to give us an original receipt from your purchases. All your travel expenses must be preapproved by the study team.

Location

Brigham and Women's Hospital
45 Francis Street, Boston, MA 02115

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Travel

  • Local travel reimbursed
  • Parking available
  • Parking reimbursed

Travel and Parking Details

Additional Information

Project Website

http://paintrials.org


Participating Institutions


Funding Source

  • Industry
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