Note: This study is currently only recruiting patients in the hospital.

If you are interested in being notified if this study begins recruiting from the general population, please use the 'I Am Interested' button below.

Do you have diabetes that doesn't fully match Type 1 or Type 2? RADIANT wants you!

RADIANT is a network of institutions across the U.S. who are studying atypical forms of diabetes. Our research staff identify people with atypical diabetes to learn more about their health.

Massachusetts General Hospital Rare Diseases Genetic Testing Diabetes
3 visits over 4 years
Estimated Time Commitment
Any Sex/Gender, Any Age
May Be Eligible
Non-payment compensation, Payment up to $240, Meals
May Be Offered
Office visit, Survey, Blood draw, Injection or IV
May Be Required
 
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This project is not recruiting.

Who can participate

You may be offered enrollment if you've been diagnosed by your doctor with diabetes, but do not fit the usual pattern of either type 1 or type 2 diabetes.


RADIANT is not able to enroll people with autoimmune diabetes (such as Latent Autoimmune Diabetes in Adulthood [LADA]) or known genetic forms of diabetes (such as Maturity Onset Diabetes of the Young [MODY]).


Detailed inclusion and exclusion criteria are available at https://www.atypicaldiabetesnetwork.org/join.

Who cannot participate

There are also factors that can exclude you from participating in our research. If you meet any of the below criteria, you may be not be eligible to participate:



  • High likelihood of typical type 1, typical type 2, known monogenic, or other known secondary forms of diabetes

  • Those who do not want to have genetic testing

  • Those who are have positive diabetes autoantibodies. (Participants with positive autoantibodies
    who also have atypical features, i.e. syndromic, strong linear family history of diabetes, may not be
    excluded)

  • Women who are currently pregnant

What you may be asked to do

At a minimum, you will be asked to provide your name and a method of contact. You will also be asked to complete around 20 screening questions.


If enrolled, you will be asked to do things such as complete surveys; measurements such as height, weight and blood pressure; and provide samples of blood for immunological and genetic testing. You may be asked to provide your medical and family history. (A comprehensive list of all tasks to be completed and a schedule of these tasks will be included when you join RADIANT.)


An "adjudication" committee of experts will review your test results and determine if your diabetes is "atypical" or "rare". If you do have a rare form of diabetes, you may be asked to provide some additional samples throughout the study. We will share the results of most tests with you.


This study has 3 stages, you may be invited to participate in one or all of them. You may be asked to visit one of our study centers. RADIANT will pay for travel costs. Your participation in RADIANT may last for several years.


Project activities may include:

  • Office visit
  • Survey
  • Blood draw
  • Injection or IV

Estimated Time Commitment

3 visits over 4 years

What You May Get

Patients eligible for the study will receive free clinical-grade whole genome sequencing with a results report returned to them. You may learn more about what type of diabetes you have and whether you have a rare or atypical form of diabetes. By participating, you will also be helping us better understand all types of diabetes.

Location

MGH Diabetes Research Center
50 Staniford Street, 3rd Floor Suite 301, Boston, MA 02114

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Travel

  • Accessible by public transportation
  • Parking available
  • Parking reimbursed
  • Out of state travel possibly reimbursed

Travel and Parking Details

Additional Information

Project Website

https://www.atypicaldiabetesnetwork.org/


Participating Institutions


Funding Source

  • NIH or Other Federal
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