Note: This study is currently only recruiting patients in the hospital.

If you are interested in being notified if this study begins recruiting from the general population, please use the 'I Am Interested' button below.

Do you have heart disease?

We are studying which of two flu vaccines, the standard dose or a higher dose, is more effective in reducing deaths and heart- or lung-related visits to the hospital in people with heart disease.

Brigham and Women's Hospital Flu Shot Heart Diseases Heart Failure
1 hour
Estimated Time Commitment
Any Gender, 18-years or older
May Be Eligible
Gift card up to $25
May Be Offered
Injection or IV, Office visit
May Be Required
 
I Am Interested I Am Interested I Am Interested

This project is not recruiting.

Overview

What we are studying

We are studying which of two formulations of influenza vaccine, the standard dose or an investigational higher dose, is more effective in reducing deaths and heart– or lung-related admissions to the hospital in patients with heart disease.


Why it is important

The flu can lead to complications like hospitalizations and/or death, particularly in patients with heart disease. In fact, influenza-related death is more common in people with heart disease than any other chronic health condition. 


What we hope to accomplish

Research findings based on INVESTED may benefit future patients by helping us understand whether a high dose or standard dose influenza “flu” vaccine is better for those with heart disease.

Principal Investigator

Michael Givertz, MD

Brigham and Women's Hospital

Public Profile

Who can participate

You may qualify to take part in the research study if:



  • You have been hospitalized for heart failure in the past two years

  • You have been hospitalized for a heart attack in the past year

  • Are 18 years of age or older

Who cannot participate

You may not participate if:



  • You are younger than 18 years old

  • You have already had you flu shot for this year

  • You have had an allergic reaction to the flu vaccine

  • You are pregnant or breastfeeding

What you may be asked to do


  • Complete a one hour visit where you will be asked about your medical history and given a flu vaccine

  • Allow us to contact you by phone one week after your visit to ask you some medical questions

  • Allow us to call you twice, once in the spring and once in the summer to ask about medical events since your vaccination


 


Project activities may include:

  • Injection or IV
  • Office visit

Estimated Time Commitment

1 hour

What You May Get


  • $25 for participating in the trial

  • Parking voucher if you are coming to BWH solely for the study visit

Location


Travel

  • Parking reimbursed
  • Accessible by public transportation

Travel and Parking Details

Additional Information

Project Website

http://www.investedtrial.org/


ClinicalTrials.gov Identifier

NCT02787044


Study Phase

Phase 4: This project studies a drug or treatment that has already been approved by the FDA and studied in both healthy volunteers and participants with specific diseases or conditions. It will gather more information about long term safety and will help to understand how the drug or treatment can be most effective.


Participating Institutions


Funding Source

  • NIH or Other Federal
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